AMD introduces Helion racks for AI agents, with up to 32,768 CPU cores and optional GPUs

AMD Helion agentic AI rack

Image: AMD

Key points

  • What goes inside a Helion rack
  • How Helion differs from Helios
  • Why Microsoft is still buying CPUs

Advanced Micro Devices (AMD) introduced Helion on Monday, October 12, a rack design for running AI agents that comes in CPU-only and CPU-plus-GPU versions. The CPU-only configuration supports up to 32,768 cores, and partner-built systems based on both designs are planned for November 2026.

AMD unveiled Helion at the Open Compute Project Summit in San Jose, California, calling it "an open blueprint for agentic AI infrastructure." Dell Technologies, HPE, Lenovo, Supermicro, and Cisco are among its partners.

Helion provides the specifications for partners to build their own systems. AMD plans to contribute the design to the Open Compute Project, which shares open data center hardware designs.

Helion comes in CPU-only and CPU-plus-GPU versions

Helion is designed for the work agents do around AI models, such as running code and managing tasks. The model inference itself can run on separate systems or on GPUs inside the rack.

The CPU-only version is built for hyperscalers and uses 6th Gen EPYC processors. AMD says it provides "dedicated capacity for agent execution and connections to separate model inference infrastructure." Customers can mix different CPU server configurations in one rack, up to the 32,768-core maximum.

The enterprise version adds up to 16 Instinct MI350P GPUs, in two eight-GPU servers that run independently. AMD says there's no high-speed link joining the two because the rack isn't meant for frontier-scale training. The rack supports up to 102 terabits per second of networking bandwidth and comes in liquid-cooled and air-cooled designs.

The enterprise version also uses what AMD calls a token router, which sends an agent's requests either to frontier models running in the cloud or to open-source models running inside the same rack. Cloud model calls are typically billed by usage. Running models locally shifts costs toward hardware, power, and operations. AMD didn't quantify potential savings from routing between the two.

"Agentic AI is not a single workload. It spans personal agents, enterprise applications, code execution and complex workflows, each with different compute requirements," said Dan McNamara, AMD's senior vice president and general manager of Compute and Enterprise AI.

Helion is separate from AMD's Helios GPU rack

The name is one letter off from Helios, the GPU rack AMD launched earlier this year, which The Register said is "inviting confusion a little." HPE landed a $1.2 billion Vultr order for Helios racks last month.

AMD's product page says the two don't compete. Helios links GPUs into a tightly connected system for large-scale training and inference. Helion focuses on running agents, with optional local inference.

The launch came the same day Microsoft (MSFT) said it would make its own Maia chips the main AI inference system for its products. Microsoft cloud chief Scott Guthrie said in an interview published Monday that long-running agents are driving "a huge rise in terms of the need for CPUs." Microsoft is ramping its own Cobalt CPUs, he said, "but we're still going to buy a bunch of AMD and Intel CPUs as well."

AMD shares were down 2.5% at $592.67 as of 11:59 a.m. ET.

Frequently asked questions

What is AMD Helion?

AMD Helion is an open rack reference design for running AI agents that AMD (AMD) introduced on October 12, 2026. A CPU-only version holds up to 32,768 Zen 6 CPU cores, and an enterprise version adds up to 16 Instinct MI350P GPUs. Partner-built systems are planned for November 2026.

Is AMD Helion the same as AMD Helios?

No. Helios is AMD's rack for frontier-scale AI training and large-scale inference. Helion is a separate design for running AI agents, built mainly around EPYC CPUs, with optional GPU servers for inference. AMD says the two do not compete.

Which companies support AMD Helion?

AMD's announcement includes support from Cisco, Dell Technologies, Hon Hai Technology Group, HPE, Lenovo, QCT, Supermicro, and Wiwynn. AMD plans to contribute the Helion specification to the Open Compute Project.

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Dennis Singleton
Dennis Singleton

Dennis Singleton was born in Australia and later moved to the United States. He has spent years following the markets, but what keeps his attention is how AI is built. He writes about the companies behind the technology, from semiconductor designers and advanced packaging to photonics, memory, networking, and the hardware powering modern AI. His approach starts with filings, earnings, and industry research, then translates the important details into clear, straightforward analysis without unnecessary hype.